Biosciences at UCLA
Cores and Resources Serving UCLA
Christopher Logg, Ph.D.

Email Address:
logg@ucla.edu

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Department / Division Affiliations
Associate Director, UCLA Vector Core
Assistant Adjunct Professor, Medicine
Publications:

Logg Christopher R, Robbins Joan M, Jolly Douglas J, Gruber Harry E, Kasahara Noriyuki Retroviral replicating vectors in cancer.. Methods in Enzymology. 2012; 507: 199-228.
Kimura Takahiro, Hiraoka Kei, Kasahara Noriyuki, Logg Christopher R Optimization of enzyme-substrate pairing for bioluminescence imaging of gene transfer using Renilla and Gaussia luciferases.. Journal of Gene Medicine. 2010; 12(6): 528-37.
Tai C-K, Wang W, Lai Y-H, Logg CR, Parker WB, Li Y-F, Hong JS, Sorscher EJ, Chen TC, Kasahara N Enhanced efficiency of prodrug activation therapy by tumor-selective replicating retrovirus vectors armed with the Escherichia coli purine nucleoside phosphorylase gene.. Cancer Gene Therapy. 2010; 17(9): 614-23.
Haga Kazunori, Tomioka Atsushi, Liao Chun-Peng, Kimura Takahiro, Matsumoto Hiroshi, Ohno Izumi, Hermann Kip, Logg Christopher R, Jiao Jing, Tanaka Motoyoshi, Hirao Yoshihiko, Wu Hong, Kruse Carol A, Roy-Burman Pradip, Kasahara Noriyuki PTEN knockout prostate cancer as a model for experimental immunotherapy.. Journal of Urology. 2009; 181(1): 354-62.
Baranick Brian T, Lemp Nathan A, Nagashima Jill, Hiraoka Kei, Kasahara Noriyuki, Logg Christopher R Splicing mediates the activity of four putative cellular internal ribosome entry sites.. Proceedings of the National Academy of Sciences of the United States of America. 2008; 105(12): 4733-8.
Logg Christopher R, Baranick Brian T, Lemp Nathan A, Kasahara Noriyuki Adaptive evolution of a tagged chimeric gammaretrovirus: identification of novel cis-acting elements that modulate splicing.. Journal of Molecular Biology. 2007; 369(5): 1214-29.
Kikuchi Eiji, Menendez Silvia, Ozu Choichiro, Ohori Makoto, Cordon-Cardo Carlos, Logg Christopher R, Kasahara Noriyuki, Bochner Bernard H Highly efficient gene delivery for bladder cancers by intravesically administered replication-competent retroviral vectors.. Clinical Cancer Research. 2007; 13(15 Pt 1): 4511-8.
Hiraoka Kei, Kimura Takahiro, Logg Christopher R, Tai Chien-Kuo, Haga Kazunori, Lawson Gregory W, Kasahara Noriyuki Therapeutic efficacy of replication-competent retrovirus vector-mediated suicide gene therapy in a multifocal colorectal cancer metastasis model.. Cancer Research. 2007; 67(11): 5345-53.
Kikuchi E, Menendez S, Ozu C, Ohori M, Cordon-Cardo C, Logg CR, Kasahara N, Bochner BH Delivery of replication-competent retrovirus expressing Escherichia coli purine nucleoside phosphorylase increases the metabolism of the prodrug, fludarabine phosphate and suppresses the growth of bladder tumor xenografts.. Cancer Gene Therapy. 2007; 14(3): 279-86.
Haga K, Lemp NA, Logg CR, Nagashima J, Faure-Kumar E, Gomez GG, Kruse CA, Mendez R, Stripecke R, Kasahara N, Kasahara N, Cicciarelli JC Permanent, lowered HLA class I expression using lentivirus vectors with shRNA constructs: Averting cytotoxicity by alloreactive T lymphocytes.. Transplantation Proceedings. 2006; 38(10): 3184-8.
Hiraoka Kei, Kimura Takahiro, Logg Christopher R, Kasahara Noriyuki Tumor-selective gene expression in a hepatic metastasis model after locoregional delivery of a replication-competent retrovirus vector.. Clinical Cancer Research. 2006; 12(23): 7108-16.
Dalba Charlotte, Klatzmann David, Logg Christopher R, Kasahara Noriyuki Beyond oncolytic virotherapy: replication-competent retrovirus vectors for selective and stable transduction of tumors.. Current Gene Therapy. 2005; 5(6): 655-67.
Logg Christopher R, Kasahara Noriyuki Retrovirus-mediated gene transfer to tumors: utilizing the replicative power of viruses to achieve highly efficient tumor transduction in vivo.. Methods in Molecular Biology. 2004; 246(3): 499-525.
Tai Chien-Kuo, Logg Christopher R, Park Jinha M, Anderson W French, Press Michael F, Kasahara Noriyuki Antibody-mediated targeting of replication-competent retroviral vectors.. Human Gene Therapy. 2003; 14(8): 789-802.
Logg CR, Logg A, Matusik RJ, Bochner BH, Kasahara N Tissue-specific transcriptional targeting of a replication-competent retroviral vector.. Journal of Virology. 2002; 76(24): 12783-91.
Soifer Harris, Higo Collin, Logg Christopher R, Jih Lily Ja-Lu, Shichinohe Toshiaki, Harboe-Schmidt Erik, Mitani Kohnosuke, Kasahara Noriyuki A novel, helper-dependent, adenovirus-retrovirus hybrid vector: stable transduction by a two-stage mechanism.. Molecular Therapy. 2002; 5(5 Pt 1): 599-608.
Chang Z, Pan J, Logg C, Kasahara N, Roy-Burman P A replication-competent feline leukemia virus, subgroup A (FeLV-A), tagged with green fluorescent protein reporter exhibits in vitro biological properties similar to those of the parental FeLV-A.. Journal of Virology. 2001; 75(18): 8837-41.
Logg CR, Logg A, Tai CK, Cannon PM, Kasahara N Genomic stability of murine leukemia viruses containing insertions at the Env-3' untranslated region boundary.. Journal of Virology. 2001; 75(15): 6989-98.
Logg CR, Tai C K, Logg A, Anderson WF, Kasahara N A uniquely stable replication-competent retrovirus vector achieves efficient gene delivery in vitro and in solid tumors.. Human Gene Therapy. 2001; 12(8): 921-32.
Smith E, Redman RA, Logg CR, Coetzee GA, Kasahara N, Frenkel B Glucocorticoids inhibit developmental stage-specific osteoblast cell cycle. Dissociation of cyclin A-cyclin-dependent kinase 2 from E2F4-p130 complexes.. The Journal of Biological Chemistry. 2000; 275(26): 19992-20001.