Kent Taylor, PhD is Laboratory Operations Director of the General Clinical Research Center's Phenotyping/Genotyping Laboratory at Cedars-Sinai. Dr. Taylor is also a member of the Genetics of Common Diseases Group at Cedars-Sinai's Medical Genetics-Birth Defects Center.
Dr. Taylor provides genotyping data and bioinformatics support to the Genetics of Common Diseases Group and to various clinical investigators at Cedars-Sinai Medical Center. He studies the genetics of inflammatory bowel disease as a member of the Immunobiology Center.
Dr. Taylor previously studied the control of gene expression from both the nuclear and mitochondrial genome in early preimplantation mouse development with Dr. Lajos Piko at the research center of the Veterans Administration Hospital in Sepulveda, California. At Cedars-Sinai he continues this interest in the interactions between the mitochondrial and nuclear genome with his studies of the role of mitochondrial mutations in Type 2 diabetes mellitus (T2DM) within the Hispanic population of Los Angeles.
In addition to mitochondria, Dr. Taylor's research interests include gene identification in complex genetic traits, including T2DM, hypertension, coronary artery disease, inflammatory bowel disease and keratoconus, as well as pharmacogenetics - studying how genetic changes affect drug response.
Dr. Taylor earned his doctorate in molecular biology from University of Southern California in Los Angeles.
Shrestha Sadeep, Irvin Marguerite R, Taylor Kent D, Wiener Howard W, Pajewski Nicholas M, Haritunians Talin, Delaney Joseph A C, Schambelan Morris, Polak Joseph F, Arnett Donna K, Chen Yii-Der Ida, Grunfeld Carl,
A genome-wide association study of carotid atherosclerosis in
HIV-infected men..
AIDS (London, England).
2010; 24(4):
583-92.
Wassel Christina L, Pankow James S, Rasmussen-Torvik Laura J, Li Na, Taylor Kent D, Guo Xiuqing, Goodarzi Mark O, Palmas Walter R, Post Wendy S,
Associations of SNPs in ADIPOQ and Subclinical Cardiovascular Disease
in the Multi-Ethnic Study of Atherosclerosis (MESA)..
Obesity (Silver Spring, Md.).
2010; 116(20):
.
McGovern Dermot P B, Jones Michelle R, Taylor Kent D, Marciante Kristin, Yan Xiaofei, Dubinsky Marla, Ippoliti Andy, Vasiliauskas Eric, Berel Dror, Derkowski Carrie, Dutridge Deb, Fleshner Phil, Shih David Q, Melmed Gil, Mengesha Emebet, King Lily, Pressman Sheila, Haritunians Talin, Guo Xiuqing, Targan Stephan R, Rotter Jerome I, Rotter Jerome I,
Fucosyltransferase 2 (FUT2) non-secretor status is associated with
Crohn's disease..
Human molecular genetics.
2010; 19(17):
3468-76.
Haritunians Talin, Taylor Kent D, Targan Stephan R, Dubinsky Marla, Ippoliti Andrew, Kwon Soonil, Guo Xiuqing, Melmed Gil Y, Berel Dror, Mengesha Emebet, Psaty Bruce M, Glazer Nicole L, Vasiliauskas Eric A, Rotter Jerome I, Fleshner Phillip R, McGovern Dermot P B,
Genetic predictors of medically refractory ulcerative colitis..
Inflammatory bowel diseases.
2010; 16(11):
1830-40.
McGovern Dermot P B, Gardet Agnčs, Törkvist Leif, Goyette Philippe, Essers Jonah, Taylor Kent D, Neale Benjamin M, Ong Rick T H, Lagacé Caroline, Li Chun, Green Todd, Stevens Christine R, Beauchamp Claudine, Fleshner Phillip R, Carlson Marie, D'Amato Mauro, Halfvarson Jonas, Hibberd Martin L, Lördal Mikael, Padyukov Leonid, Andriulli Angelo, Colombo Elisabetta, Latiano Anna, Palmieri Orazio, Bernard Edmond-Jean, Deslandres Colette, Hommes Daan W, de Jong Dirk J, Stokkers Pieter C, Weersma Rinse K, Weersma Rinse K, Sharma Yashoda, Silverberg Mark S, Cho Judy H, Wu Jing, Roeder Kathryn, Brant Steven R, Schumm L Phillip, Duerr Richard H, Dubinsky Marla C, Glazer Nicole L, Haritunians Talin, Ippoliti Andy, Melmed Gil Y, Siscovick David S, Vasiliauskas Eric A, Targan Stephan R, Annese Vito, Wijmenga Cisca, Pettersson Sven, Rotter Jerome I, Xavier Ramnik J, Daly Mark J, Rioux John D, Seielstad Mark,
Genome-wide association identifies multiple ulcerative colitis
susceptibility loci..
Nature genetics.
2010; 42(4):
332-7.
Chalasani Naga, Guo Xiuqing, Loomba Rohit, Goodarzi Mark O, Haritunians Talin, Kwon Soonil, Cui Jinrui, Taylor Kent D, Wilson Laura, Cummings Oscar W, Chen Yii-Der Ida, Rotter Jerome I, Rotter Jerome I,
Genome-wide association study identifies variants associated with
histologic features of nonalcoholic Fatty liver disease..
Gastroenterology.
2010; 139(5):
1567-76, 1576.e1-6.
Engelman Corinne D, Meyers Kristin J, Ziegler Julie T, Taylor Kent D, Palmer Nicholette D, Haffner Steven M, Fingerlin Tasha E, Wagenknecht Lynne E, Rotter Jerome I, Bowden Donald W, Langefeld Carl D, Norris Jill M,
Genome-wide association study of vitamin D concentrations in Hispanic
Americans: the IRAS family study..
The Journal of steroid biochemistry and molecular biology.
2010; 122(4):
186-92.
McGovern Dermot P B, Rotter Jerome I, Mei Ling, Haritunians Talin, Landers Carol, Derkowski Carrie, Dutridge Deb, Dubinsky Marla, Ippoliti Andy, Vasiliauskas Eric, Mengesha Emebet, King Lily, Pressman Sheila, Targan Stephan R, Taylor Kent D,
Genetic epistasis of IL23/IL17 pathway genes in Crohn's disease..
Inflammatory bowel diseases.
2009; 15(6):
883-9.
Ikram M Arfan, Seshadri Sudha, Bis Joshua C, Fornage Myriam, DeStefano Anita L, Aulchenko Yurii S, Debette Stephanie, Lumley Thomas, Folsom Aaron R, van den Herik Evita G, Bos Michiel J, Beiser Alexa, Cushman Mary, Launer Lenore J, Shahar Eyal, Struchalin Maksim, Du Yangchun, Glazer Nicole L, Rosamond Wayne D, Rivadeneira Fernando, Kelly-Hayes Margaret, Lopez Oscar L, Coresh Josef, Hofman Albert, DeCarli Charles, Heckbert Susan R, Koudstaal Peter J, Yang Qiong, Smith Nicholas L, Kase Carlos S, Rice Kenneth, Haritunians Talin, Roks Gerwin, de Kort Paul L M, Taylor Kent D, de Lau Lonneke M, Oostra Ben A, Uitterlinden Andre G, Rotter Jerome I, Boerwinkle Eric, Psaty Bruce M, Mosley Thomas H, van Duijn Cornelia M, Breteler Monique M B, Longstreth W T, Wolf Philip A,
Genomewide association studies of stroke..
The New England journal of medicine.
2009; 360(17):
1718-28.
McGovern Dermot P B, Taylor Kent D, Landers Carol, Derkowski Carrie, Dutridge Deb, Dubinsky Marla, Ippoliti Andy, Vasiliauskas Eric, Mei Ling, Mengesha Emebet, King Lily, Pressman Sheila, Targan Stephan R, Rotter Jerome I,
MAGI2 genetic variation and inflammatory bowel disease..
Inflammatory bowel diseases.
2009; 15(1):
75-83.
Rioux John D, Xavier Ramnik J, Taylor Kent D, Silverberg Mark S, Goyette Philippe, Huett Alan, Green Todd, Kuballa Petric, Barmada M Michael, Datta Lisa Wu, Shugart Yin Yao, Griffiths Anne M, Targan Stephan R, Ippoliti Andrew F, Bernard Edmond-Jean, Mei Ling, Nicolae Dan L, Regueiro Miguel, Schumm L Philip, Steinhart A Hillary, Rotter Jerome I, Duerr Richard H, Cho Judy H, Daly Mark J, Brant Steven R,
Genome-wide association study identifies new susceptibility loci for
Crohn disease and implicates autophagy in disease pathogenesis..
Nature genetics.
2007; 39(5):
596-604.
Duerr Richard H, Taylor Kent D, Brant Steven R, Rioux John D, Silverberg Mark S, Daly Mark J, Steinhart A Hillary, Abraham Clara, Regueiro Miguel, Griffiths Anne, Dassopoulos Themistocles, Bitton Alain, Yang Huiying, Targan Stephan, Datta Lisa Wu, Kistner Emily O, Schumm L Philip, Lee Annette T, Gregersen Peter K, Barmada M Michael, Rotter Jerome I, Nicolae Dan L, Cho Judy H,
A genome-wide association study identifies IL23R as an inflammatory
bowel disease gene..
Science (New York, N.Y.).
2006; 314(5804):
1461-3.
