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Stephen Cederbaum, M.D.

Home:
scederbaum@mednet.ucla.edu

Mailing Address:
635 Charles E. Young Dr. South
Los Angeles, CA 90095
UNITED STATES

Department / Division Affiliations

Professor, Human Genetics, Pediatrics

Director, Medical Genetics Clinic, Metabolic Clinic

Associate Director, Mental Retardation Research Center

Bio:

Stephen Cederbaum was born in Brooklyn, NY. After graduating from Midwood High School, he attended Amherst College and received a BA degree with honors in Chemistry. He graduated from NYU School of Medicine in 1964 with honors in Biochemistry and was elected to Alpha Omega Alpha. He was an intern and resident in Internal Medicine at Barnes Hospital and Washington University School of Medicine. After two years at the National Heart Institute in Bethesda, he received medical genetics training at the University of Washington. He has been at UCLA since 1971. He sees patients with genetic and metabolic disorders, has a research laboratory and is active in teaching and training. He is married, has two grown children and lives in Santa Monica, CA.

Publications:

Cederbaum, SD New frontiers in hereditary metabolic disease: An historical perspective.. Mol. Genet. Metab.. 2006; In press: .

Deignan J.L., Yoo, P.K., Livesay J.C., Goodman S.I., O'Brien, W.E., Iyer, R.K., Cederbaum, S.D. and Grody, W.W. "Amino acids in arginase double knockout mice demonstrate ornithine auxotrophy". Mol. Genet. Metab. 2006; 89: 87-96.

Crombez, EA Cederbaum, SD Hyperargininemia due to liver arginase deficiency.. Molecular genetics and metabolism. . 2005; 84(3): 243-51.

Becker-Catania, S.G., Gregory, T.L., Yang, Y., Gau, C-L., de Vellis, J., Cederbaum, S.D. and Iyer, R.K. "Loss of arginase I results in increased proliferation of neural progenitor cells". J. Neurosci.Res. 2006; 84: 735-746.

Cederbaum, SD Yu, H Grody, WW Kern, RM Yoo, P Iyer, RK Arginases I and II: do their functions overlap?. Molecular genetics and metabolism. . 2004; 81 Suppl 1: S38-44.

Svitanovic Sojat, L., Tein, I, Lamhonwah, A-M., De Meirleir, L., Cederbaum, S.D., Jurcic, Z, Mucic-Pucic, B. and Lukanovic-Novak, T. "Fourteen-year follow up of a girl with primary systemic carnitine due to a carnitine transporter defect and OCTN2 mutation". Paediatr. Croat. 47 2003; 83-86.

Hewson, S Clarke, JT Cederbaum, S Prenatal diagnosis for arginase deficiency: a case study.. Journal of inherited metabolic disease. . 2003; 26(6): 607-10.

Yu, H Yoo, PK Aguirre, CC Tsoa, RW Kern, RM Grody, WW Cederbaum, SD Iyer, RK Widespread expression of arginase I in mouse tissues. Biochemical and physiological implications.. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. . 2003; 51(9): 1151-60.

Iyer, RK Yoo, PK Kern, RM Rozengurt, N Tsoa, R O'Brien, WE Yu, H Grody, WW Cederbaum, SD Mouse model for human arginase deficiency.. Molecular and cellular biology. . 2002; 22(13): 4491-8.

Yu, H Iyer, RK Yoo, PK Kern, RM Grody, WW Cederbaum, SD Arginase expression in mouse embryonic development.. Mechanisms of development. . 2002; 115(1-2): 151-5.

Mardach, R., Zempleni, J., Wolf, B., Cannon, M.J., Jennings, M.L., Cress, S., Boylan, J., Roth, S., Cederbaum, S. and Mock, D. "Biotin dependency due to a defect in biotin transport". J. Clin. Invest. 109 2002; 1617-1623.

Iyer, RK Kim, HK Tsoa, RW Grody, WW Cederbaum, SD Cloning and characterization of human agmatinase.. Molecular genetics and metabolism. . 2002; 75(3): 209-18.

Kim, PS Iyer, RK Lu, KV Yu, H Karimi, A Kern, RM Tai, DK Cederbaum, SD Grody, WW Expression of the liver form of arginase in erythrocytes.. Molecular genetics and metabolism. . 2002; 76(2): 100-10.

Gobert, AP Cheng, Y Wang, JY Boucher, JL Iyer, RK Cederbaum, SD Casero, RA Newton, JC Wilson, KT Helicobacter pylori induces macrophage apoptosis by activation of arginase II.. Journal of immunology (Baltimore, Md. : 1950) . 2002; 168(9): 4692-700.

Nguyen, TV Andresen, BS Corydon, TJ Ghisla, S Abd-El Razik, N Mohsen, AW Cederbaum, SD Roe, DS Roe, CR Lench, NJ Vockley, J Identification of isobutyryl-CoA dehydrogenase and its deficiency in humans.. Molecular genetics and metabolism. . 2002; 77(1-2): 68-79.

Gobin, S Bonnefont, JP Prip-Buus, C Mugnier, C Ferrec, M Demaugre, F Saudubray, JM Rostane, H Djouadi, F Wilcox, W Cederbaum, S Haas, R Nyhan, WL Green, A Gray, G Girard, J Thuillier, L Organization of the human liver carnitine palmitoyltransferase 1 gene ( CPT1A) and identification of novel mutations in hypoketotic hypoglycaemia.. Human genetics. . 2002; 111(2): 179-89.

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