Genetic epidemiology of epilepsy and other neurological disorders, post traumatic stress disorder and schizophrenia. Focus on gene localization through family-based linkage and association methods as well as next generation deep sequencing technology
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Dr. Bailey became interested in evolutionary biology and statistical genetics during her first degree working with insects. In graduate school she started studying Epidemiology and Human genetics. Most of her career has been focused on methods to find genes for complex traits using large extended pedigrees. These large, extended families allow the study of co-segregation of specific DNA and the clinical and subclinical phenotypes.
Dr. Bailey studies families collected from various countries including Honduras, Mexico, Armenia and the United States, some families have over 100 members and more than 9 affected members.
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Kazma, R and Bailey, JN Population-based and Family-based Designs to Analyze Rare Variants in Complex Diseases.
Genetic Epidemiology
2011; Vol 35, Supplement 8(In Press):
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Bailey Julia N, Goenjian Armen K, Noble Ernest P, Walling David P, Ritchie Terry, Goenjian Haig A PTSD and dopaminergic genes, DRD2 and DAT, in multigenerational
families exposed to the Spitak earthquake..
Psychiatry research.
2010; 178(3):
507-10.
Tanaka Miyabi, Olsen Richard W, Medina Marco T, Schwartz Emily, Alonso Maria Elisa, Duron Reyna M, Castro-Ortega Ramon, Martinez-Juarez Iris E, Pascual-Castroviejo Ignacio, Machado-Salas Jesus, Silva Rene, Bailey Julia N, Bai Dongsheng, Ochoa Adriana, Jara-Prado Aurelio, Pineda Gregorio, Macdonald Robert L, Delgado-Escueta Antonio V Hyperglycosylation and reduced GABA currents of mutated GABRB3
polypeptide in remitting childhood absence epilepsy..
American journal of human genetics.
2008; 82(6):
1249-61.
Goenjian Armen K, Bailey Julia N, Walling David P, Steinberg Alan M, Schmidt Devon, Dandekar Uma, Noble Ernest P Association of TPH1, TPH2, and 5HTTLPR with PTSD and depressive
symptoms..
Journal of affective disorders.
2012; 140(3):
244-52.
Bai Dongsheng, Bailey Julia N, Durón Reyna M, Alonso María E, Medina Marco T, Martínez-Juárez Iris E, Suzuki Toshimitsu, Machado-Salas Jesús, Ramos-Ramírez Ricardo, Tanaka Miyabi, Ortega Ramón H Castro, López-Ruiz Minerva, Rasmussen Astrid, Ochoa Adriana, Jara-Prado Aurelio, Yamakawa Kazuhiro, Delgado-Escueta Antonio V DNA variants in coding region of EFHC1: SNPs do not associate with
juvenile myoclonic epilepsy..
Epilepsia.
2009; 50(5):
1184-90.
Fairbanks Lynn A, Jorgensen Matthew J, Bailey Julia N, Breidenthal Sherry E, Grzywa Rachel, Laudenslager Mark L Heritability and genetic correlation of hair cortisol in vervet
monkeys in low and higher stress environments..
Psychoneuroendocrinology.
2011; 36(8):
1201-8.
Goenjian Armen K, Noble Ernest P, Walling David P, Goenjian Haig A, Karayan Ida S, Ritchie Terry, Bailey Julia N Heritabilities of symptoms of posttraumatic stress disorder, anxiety,
and depression in earthquake exposed Armenian families..
Psychiatric genetics.
2008; 18(6):
261-6.
Jara-Prado Aurelio, Martínez-Juárez Iris E, Ochoa Adriana, González Víctor M, Fernández-González-Aragón María Del Carmen, López-Ruiz Minerva, Medina Marco T, Bailey Julia N, Delgado-Escueta Antonio V, Alonso María Elisa Novel Myoclonin1/EFHC1 mutations in Mexican patients with juvenile
myoclonic epilepsy..
Seizure : the journal of the British Epilepsy Association.
2012; 21(7):
550-4.
Medina M T, Suzuki T, Alonso M E, Durón R M, Martínez-Juárez I E, Bailey J N, Bai D, Inoue Y, Yoshimura I, Kaneko S, Montoya M C, Ochoa A, Prado A Jara, Tanaka M, Machado-Salas J, Fujimoto S, Ito M, Hamano S, Sugita K, Ueda Y, Osawa M, Oguni H, Rubio-Donnadieu F, Yamakawa K, Delgado-Escueta A V Novel mutations in Myoclonin1/EFHC1 in sporadic and familial juvenile
myoclonic epilepsy..
Neurology.
2008; 70(22 Pt 2):
2137-44.
Fairbanks L A, Bailey J N, Breidenthal S E, Laudenslager M L, Kaplan J R, Jorgensen M J Environmental stress alters genetic regulation of novelty seeking in
vervet monkeys..
Genes, brain, and behavior.
2011; 10(6):
683-8.
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